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查看说明书Recombinant Human Coagulation Factor IX/F9 Protein(C-6His)
Cat#:TP05031应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Factor IX/PTC Rabbit pAb |
| Cat No.: | DPA01444 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IP |
| Recommended Dilution: | WB: 1:1000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Factor IX/PTC |
| Calculated Molecular Weight: | 52 kDa |
| Observed Molecular Weight: | 52 kDa |
| GenBank Accession Number: | P00740 |
| Gene ID (NCBI): | 2158 |
| Synonyms: | FIX; P19; PTC; HEMB; THPH8; F9 p22 |
| Background: | This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Sep 2015] |
| Category: | Primary Ab |
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