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TIM 3 Rabbit pAb

Cat No.: DPA01535
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Product Name: TIM 3 Rabbit pAb
Cat No.: DPA01535
Clonality: Polyclonal
Species Reactivity: Human, Mouse
Tested Applications: WB,IHC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:100
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human TIM 3
Calculated Molecular Weight: 33 kDa
Observed Molecular Weight: 45-70 kDa
GenBank Accession Number: Q8TDQ0
Gene ID (NCBI): 84868
Synonyms: TIM3; CD366; KIM-3; SPTCL; TIMD3; Tim-3; TIMD-3; HAVcr-2
Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. [provided by RefSeq, Sep 2011]
Category: Primary Ab
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