Recombinant Human Carbonic Anhydrase IX / CA9 Protein (Fc tag)
Cat#:TP06400应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Carbonic Anhydrase 9/CA9 Rabbit pAb |
Cat No.: | DPA01625 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,IP |
Recommended Dilution: | WB: 1:1000 IHC: 1:200 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Carbonic Anhydrase 9/CA9 |
Calculated Molecular Weight: | 50 kDa |
Observed Molecular Weight: | 50 kDa |
GenBank Accession Number: | Q16790 |
Gene ID (NCBI): | 768 |
Synonyms: | MN; CAIX |
Background: | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jun 2014] |
Category: | Primary Ab |