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查看说明书Recombinant Cyclin Dependent Kinase Inhibitor 1B (CDKN1B)
Cat#:TP05814应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | p27 KIP 1 Rabbit pAb |
| Cat No.: | DPA01658 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human p27 KIP 1 |
| Calculated Molecular Weight: | 22 kDa |
| Observed Molecular Weight: | 27 kDa |
| GenBank Accession Number: | P46527 |
| Gene ID (NCBI): | 1027 |
| Synonyms: | KIP1; MEN4; CDKN4; MEN1B; P27KIP1 |
| Background: | This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014] |
| Category: | Primary Ab |
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