Recombinant Human HBG1 Protein
Cat#:TP02409应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | fetal hemoglobin Rabbit pAb |
Cat No.: | DPA01804 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human fetal hemoglobin |
Calculated Molecular Weight: | 16 kDa |
Observed Molecular Weight: | 16 kDa |
GenBank Accession Number: | P69891 |
Gene ID (NCBI): | 3047 |
Synonyms: | HBGA; HBGR; HBG-T2; HSGGL1; PRO2979 |
Background: | The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |