蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书SERCA2 ATPase Rabbit pAb
Cat#:DPA01131应用：WB,IHC,ICC/IF,FC
| Product Name: | SERCA2 ATPase Rabbit pAb |
| Cat No.: | DPA01871 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human SERCA2 ATPase |
| Calculated Molecular Weight: | 115 kDa |
| Observed Molecular Weight: | 115 kDa |
| GenBank Accession Number: | P16615 |
| Gene ID (NCBI): | 488 |
| Synonyms: | DD; DAR; ATP2B; SERCA2 |
| Background: | This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of the skeletal muscle. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol into the sarcoplasmic reticulum lumen, and is involved in regulation of the contraction/relaxation cycle. Mutations in this gene cause Darier-White disease, also known as keratosis follicularis, an autosomal dominant skin disorder characterized by loss of adhesion between epidermal cells and abnormal keratinization. Other types of mutations in this gene have been associated with various forms of muscular dystrophies. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2019] |
| Category: | Primary Ab |
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