Recombinant Human Angiotensinogen/Serpin A8/AGT Protein(C-6His)
Cat#:TP05938应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Angiotensinogen Rabbit pAb |
Cat No.: | DPA01888 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,ICC/IF,IP |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Angiotensinogen |
Calculated Molecular Weight: | 53 kDa |
Observed Molecular Weight: | 53 kDa |
GenBank Accession Number: | P01019 |
Gene ID (NCBI): | 183 |
Synonyms: | ANHU; hFLT1; SERPINA8 |
Background: | The protein encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure, body fluid and electrolyte homeostasis, and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease. [provided by RefSeq, Nov 2019] |
Category: | Primary Ab |