蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Human SKP1 Protein
Cat#:TP03954应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Skp1 Rabbit pAb |
| Cat No.: | DPA01899 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Skp1 |
| Calculated Molecular Weight: | 19 kDa |
| Observed Molecular Weight: | 19 kDa |
| GenBank Accession Number: | P63208 |
| Gene ID (NCBI): | 6500 |
| Synonyms: | OCP2; p19A; EMC19; SKP1A; OCP-II; TCEB1L |
| Background: | This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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