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Thyroid Peroxidase/TPO Rabbit pAb

Cat No.: DPA01962
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Product Name: Thyroid Peroxidase/TPO Rabbit pAb
Cat No.: DPA01962
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,IP
Recommended Dilution: WB: 1:1000
IHC: 1:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Thyroid Peroxidase/TPO
Calculated Molecular Weight: 103 kDa
Observed Molecular Weight: 103 kDa
GenBank Accession Number: P07202
Gene ID (NCBI): 7173
Synonyms: MSA; TPX; TDH2A
Background: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
Category: Primary Ab
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