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分子生物学
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查看说明书Recombinant Stanniocalcin 2 (STC2)
Cat#:TP04057应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Stanniocalcin 2/STC-2 Rabbit pAb |
| Cat No.: | DPA01984 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:20 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Stanniocalcin 2/STC-2 |
| Calculated Molecular Weight: | 33 kDa |
| Observed Molecular Weight: | 33 kDa |
| GenBank Accession Number: | O76061 |
| Gene ID (NCBI): | 8614 |
| Synonyms: | STC-2; STCRP |
| Background: | This gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression of this gene is induced by estrogen and altered in some breast cancers. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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