Recombinant Human Lck Kinase Protein (GST tag)
Cat#:TP08520应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Lck Rabbit pAb |
Cat No.: | DPA02032 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:100 FC: 1:20 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Lck |
Calculated Molecular Weight: | 58 kDa |
Observed Molecular Weight: | 58 kDa |
GenBank Accession Number: | P06239 |
Gene ID (NCBI): | 3932 |
Synonyms: | LSK; YT16; IMD22; p56lck; pp58lck |
Background: | This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016] |
Category: | Primary Ab |