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YWHAE Rabbit pAb

Cat No.: DPA02078
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Product Name: YWHAE Rabbit pAb
Cat No.: DPA02078
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,ICC/IF,FC
Recommended Dilution: WB: 1:1000
ICC/IF: 1:50
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human YWHAE
Calculated Molecular Weight: 29 kDa
Observed Molecular Weight: 29 kDa
GenBank Accession Number: P62258
Gene ID (NCBI): 7531
Synonyms: MDS; HEL2; MDCR; KCIP-1; 14-3-3E
Background: This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
Category: Primary Ab
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