Recombinant Human 14-3-3 ε/YWHAE Protein
Cat#:TP01007应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | YWHAE Rabbit pAb |
Cat No.: | DPA02078 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF,FC |
Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 FC: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human YWHAE |
Calculated Molecular Weight: | 29 kDa |
Observed Molecular Weight: | 29 kDa |
GenBank Accession Number: | P62258 |
Gene ID (NCBI): | 7531 |
Synonyms: | MDS; HEL2; MDCR; KCIP-1; 14-3-3E |
Background: | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008] |
Category: | Primary Ab |