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分子生物学
规格：
查看说明书BAP1 Rabbit pAb
Cat#:DPA02109应用：WB,FC
| Product Name: | BAP1 Rabbit pAb |
| Cat No.: | DPA02109 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,FC |
| Recommended Dilution: | WB: 1:1000 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human BAP1 |
| Calculated Molecular Weight: | 80 kDa |
| Observed Molecular Weight: | 95 kDa |
| GenBank Accession Number: | Q92560 |
| Gene ID (NCBI): | 8314 |
| Synonyms: | UCHL2; hucep-6; HUCEP-13 |
| Background: | This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma. [provided by RefSeq, May 2013] |
| Category: | Primary Ab |
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