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Junctional Adhesion Molecule 1 Rabbit pAb

Cat No.: DPA02191
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Product Name: Junctional Adhesion Molecule 1 Rabbit pAb
Cat No.: DPA02191
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human Junctional Adhesion Molecule 1/JAM-A
Calculated Molecular Weight: 33 kDa
Observed Molecular Weight: 33 kDa
GenBank Accession Number: Q9Y624
Gene ID (NCBI): 50848
Synonyms: JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1
Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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