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查看说明书Recombinant Junctional Adhesion Molecule 1 (JAM1)
Cat#:TP02065应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Junctional Adhesion Molecule 1 Rabbit pAb |
| Cat No.: | DPA02191 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:20 FC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Junctional Adhesion Molecule 1/JAM-A |
| Calculated Molecular Weight: | 33 kDa |
| Observed Molecular Weight: | 33 kDa |
| GenBank Accession Number: | Q9Y624 |
| Gene ID (NCBI): | 50848 |
| Synonyms: | JAM; KAT; JAM1; JAMA; JCAM; CD321; PAM-1 |
| Background: | Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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