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查看说明书Recombinant B-Cell CLL/Lymphoma 10 (Bcl10)
Cat#:TP01310应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Bcl10 Rabbit pAb |
| Cat No.: | DPA02272 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,ICC/IF,IP |
| Recommended Dilution: | WB: 1:1000 ICC/IF: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Bcl10 |
| Calculated Molecular Weight: | 26 kDa |
| Observed Molecular Weight: | 26 kDa |
| GenBank Accession Number: | O95999 |
| Gene ID (NCBI): | 8915 |
| Synonyms: | CLAP; mE10; CIPER; IMD37; c-E10; CARMEN |
| Background: | This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB. This protein is reported to interact with other CARD domain containing proteins including CARD9, 10, 11 and 14, which are thought to function as upstream regulators in NF-kappaB signaling. This protein is found to form a complex with MALT1, a protein encoded by another gene known to be translocated in MALT lymphoma. MALT1 and this protein are thought to synergize in the activation of NF-kappaB, and the deregulation of either of them may contribute to the same pathogenetic process that leads to the malignancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
| Category: | Primary Ab |
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