IKZF3 Rabbit pAb
Cat#:DPA02296应用:WB,IHC,ICC/IF
Product Name: | IKZF3 Rabbit pAb |
Cat No.: | DPA02296 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF |
Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human IKZF3 |
Calculated Molecular Weight: | 58 kDa |
Observed Molecular Weight: | 58 kDa |
GenBank Accession Number: | Q9UKT9 |
Gene ID (NCBI): | 22806 |
Synonyms: | AIO; AIOLOS; ZNFN1A3 |
Background: | This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. Several alternative transcripts encoding different isoforms have been described, as well as some non-protein coding variants. [provided by RefSeq, Apr 2012] |
Category: | Primary Ab |