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查看说明书Optineurin Rabbit pAb
Cat#:DPA02362应用：WB,IHC,FC
| Product Name: | Optineurin Rabbit pAb |
| Cat No.: | DPA02362 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Optineurin |
| Calculated Molecular Weight: | 66 kDa |
| Observed Molecular Weight: | 75 kDa |
| GenBank Accession Number: | Q96CV9 |
| Gene ID (NCBI): | 10133 |
| Synonyms: | NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP |
| Background: | This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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