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IGF1 Receptor Rabbit pAb

Cat No.: DPA02385
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Product Name: IGF1 Receptor Rabbit pAb
Cat No.: DPA02385
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000
ICC/IF: 1:20
FC: 1:50
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human IGF1 Receptor
Calculated Molecular Weight: 155 kDa
Observed Molecular Weight: 95 kDa
GenBank Accession Number: P08069
Gene ID (NCBI): 3480
Synonyms: IGFR; CD221; IGFIR; JTK13
Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2014]
Category: Primary Ab
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