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查看说明书Interferon Regulatory Factor 4 Rabbit pAb
Cat#:DPA02418应用：WB,IHC,IP
| Product Name: | Interferon Regulatory Factor 4 Rabbit pAb |
| Cat No.: | DPA02418 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:50 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human MUM1 |
| Calculated Molecular Weight: | 52 kDa |
| Observed Molecular Weight: | 52 kDa |
| GenBank Accession Number: | Q15306 |
| Gene ID (NCBI): | 3662 |
| Synonyms: | MUM1; LSIRF; SHEP8; NF-EM5 |
| Background: | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010] |
| Category: | Primary Ab |
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