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查看说明书Recombinant Human APEX1 Protein
Cat#:TP01189应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | APE1 Rabbit pAb |
| Cat No.: | DPA02618 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:50 FC: 1:100 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human APE1 |
| Calculated Molecular Weight: | 36 kDa |
| Observed Molecular Weight: | 36 kDa |
| GenBank Accession Number: | P27695 |
| Gene ID (NCBI): | 328 |
| Synonyms: | APE; APX; APE1; APEN; APEX; HAP1; REF1 |
| Background: | Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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