Recombinant Human Activator of Hsp90 ATPase-1 /AHA1 Protein
Cat#:TP01048应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | AHA1 Rabbit pAb |
Cat No.: | DPA02727 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IP |
Recommended Dilution: | WB: 1:1000 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human AHA1 |
Calculated Molecular Weight: | 38 kDa |
Observed Molecular Weight: | 42 kDa |
GenBank Accession Number: | O95433 |
Gene ID (NCBI): | 10598 |
Synonyms: | p38; AHA1; hAha1; C14orf3 |
Background: | Acts as a co-chaperone of HSP90AA1 (PubMed:29127155). Activates the ATPase activity of HSP90AA1 leading to increase in its chaperone activity (PubMed:29127155). Competes with the inhibitory co-chaperone FNIP1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:27353360). Competes with the inhibitory co-chaperone TSC1 for binding to HSP90AA1, thereby providing a reciprocal regulatory mechanism for chaperoning of client proteins (PubMed:29127155). |
Category: | Primary Ab |