CD3 Rabbit pAb
Cat#:DPA01008应用:WB,IHC,FC
Product Name: | CD3 epsilon Rabbit pAb |
Cat No.: | DPA02919 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,FC,IP |
Recommended Dilution: | WB: 1:2000-1:10000 FC: 1:20-1:100 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human CD3 epsilon |
Calculated Molecular Weight: | 23 kDa |
Observed Molecular Weight: | 23 kDa |
GenBank Accession Number: | P07766 |
Gene ID (NCBI): | 916 |
Synonyms: | T3E; TCRE; IMD18 |
Background: | The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |