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Hsp22 Rabbit pAb

Cat No.: DPA02990
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Product Name: Hsp22 Rabbit pAb
Cat No.: DPA02990
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF
Recommended Dilution: WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Hsp22
Calculated Molecular Weight: 22 kDa
Observed Molecular Weight: 22 kDa
GenBank Accession Number: Q9UJY1
Gene ID (NCBI): 26353
Synonyms: H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22
Background: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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