Recombinant Heat Shock Protein Beta 8 (HSPb8)
Cat#:TP02537应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Hsp22 Rabbit pAb |
Cat No.: | DPA02990 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF |
Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Hsp22 |
Calculated Molecular Weight: | 22 kDa |
Observed Molecular Weight: | 22 kDa |
GenBank Accession Number: | Q9UJY1 |
Gene ID (NCBI): | 26353 |
Synonyms: | H11; HMN2; CMT2L; DHMN2; E2IG1; HMN2A; HSP22 |
Background: | The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |