蛋白
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检测试剂盒
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分子生物学
规格：
查看说明书Recombinant Anterior Gradient 2 (AGR2)
Cat#:TP01083应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Anterior Gradient 2 Rabbit pAb |
| Cat No.: | DPA03027 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:200 ICC/IF: 1:100 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Anterior Gradient 2 |
| Calculated Molecular Weight: | 20 kDa |
| Observed Molecular Weight: | 18 kDa |
| GenBank Accession Number: | O95994 |
| Gene ID (NCBI): | 10551 |
| Synonyms: | AG2; AG-2; HPC8; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116 |
| Background: | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017] |
| Category: | Primary Ab |
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