蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Noxa Rabbit pAb
Cat#:DPA03063应用：WB
| Product Name: | Noxa Rabbit pAb |
| Cat No.: | DPA03063 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Noxa |
| Calculated Molecular Weight: | 6 kDa |
| Observed Molecular Weight: | 10 kDa |
| GenBank Accession Number: | Q13794 |
| Gene ID (NCBI): | 5366 |
| Synonyms: | APR; NOXA |
| Background: | Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1. |
| Category: | Primary Ab |
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