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RENT1 Rabbit pAb

Cat No.: DPA03135
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Product Name: RENT1 Rabbit pAb
Cat No.: DPA03135
Clonality: Polyclonal
Species Reactivity: Human, Mouse
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:2000-1:10000
IHC: 1:50
ICC/IF: 1:100
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human RENT1
Calculated Molecular Weight: 124 kDa
Observed Molecular Weight: 124 kDa
GenBank Accession Number: Q92900
Gene ID (NCBI): 5976
Synonyms: HUPF1; NORF1; RENT1; smg-2; pNORF1
Background: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Category: Primary Ab
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