RENT1 Rabbit pAb
Cat#:DPA03135应用:WB,IHC,ICC/IF,FC,IP
Product Name: | RENT1 Rabbit pAb |
Cat No.: | DPA03135 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse |
Tested Applications: | WB,IHC,ICC/IF,FC,IP |
Recommended Dilution: | WB: 1:2000-1:10000 IHC: 1:50 ICC/IF: 1:100 FC: 1:20 IP: 1:20 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human RENT1 |
Calculated Molecular Weight: | 124 kDa |
Observed Molecular Weight: | 124 kDa |
GenBank Accession Number: | Q92900 |
Gene ID (NCBI): | 5976 |
Synonyms: | HUPF1; NORF1; RENT1; smg-2; pNORF1 |
Background: | This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014] |
Category: | Primary Ab |