蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Rasgrp1 Rabbit pAb
Cat#:DPA03170应用：WB
| Product Name: | Rasgrp1 Rabbit pAb |
| Cat No.: | DPA03170 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse |
| Tested Applications: | WB |
| Recommended Dilution: | WB: 1:1000 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human Rasgrp1 |
| Calculated Molecular Weight: | 90 kDa |
| Observed Molecular Weight: | 90 kDa |
| GenBank Accession Number: | O95267 |
| Gene ID (NCBI): | 10125 |
| Synonyms: | V; RASGRP; hRasGRP1; CALDAG-GEFI; CALDAG-GEFII |
| Background: | This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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