蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书LXR alpha Rabbit pAb
Cat#:DPA03252应用：WB,IHC,ICC/IF,FC
| Product Name: | LXR alpha Rabbit pAb |
| Cat No.: | DPA03252 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human LXR alpha |
| Calculated Molecular Weight: | 50 kDa |
| Observed Molecular Weight: | 50 kDa |
| GenBank Accession Number: | Q13133 |
| Gene ID (NCBI): | 10062 |
| Synonyms: | LXRA; LXR-a; RLD-1 |
| Background: | The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
| Category: | Primary Ab |
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