蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书xCT Rabbit pAb
Cat#:DPA03261应用：WB,IP
| Product Name: | xCT Rabbit pAb |
| Cat No.: | DPA03261 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IP |
| Recommended Dilution: | WB: 1:1000-1:5000 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human xCT |
| Calculated Molecular Weight: | 55 kDa |
| Observed Molecular Weight: | 55 kDa |
| GenBank Accession Number: | Q9UPY5 |
| Gene ID (NCBI): | 23657 |
| Synonyms: | xCT; CCBR1 |
| Background: | This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc(-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death. [provided by RefSeq, Sep 2011] |
| Category: | Primary Ab |
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