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Adiponectin Rabbit pAb

Cat No.: DPA03268
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Product Name: Adiponectin Rabbit pAb
Cat No.: DPA03268
Clonality: Polyclonal
Species Reactivity: Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC
Recommended Dilution: WB: 1:1000
IHC: 1:200
ICC/IF: 1:200
FC: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of mouse Adiponectin
Calculated Molecular Weight: 26 kDa
Observed Molecular Weight: 30 kDa
GenBank Accession Number: Q60994
Gene ID (NCBI): 11450
Synonyms: Ad; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30
Background: Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Category: Primary Ab
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