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TrkA Rabbit pAb

Cat No.: DPA03367
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Product Name: TrkA Rabbit pAb
Cat No.: DPA03367
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC,ICC/IF,FC,IP
Recommended Dilution: WB: 1:1000-1:5000
IHC: 1:20
ICC/IF: 1:20
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human TrkA
Calculated Molecular Weight: 88 kDa
Observed Molecular Weight: 140 kDa
GenBank Accession Number: P04629
Gene ID (NCBI): 4914
Synonyms: MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA
Background: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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