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查看说明书Recombinant Human REN Protein
Cat#:TP03711应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | Renin Rabbit pAb |
| Cat No.: | DPA03523 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC |
| Recommended Dilution: | IHC: 1:500 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human Renin |
| Calculated Molecular Weight: | 45 kDa |
| GenBank Accession Number: | P00797 |
| Gene ID (NCBI): | 5972 |
| Synonyms: | HNFJ2 |
| Background: | Renin catalyzes the first step in the activation pathway of angiotensinogen--a cascade that can result in aldosterone release,vasoconstriction, and increase in blood pressure. Renin, an aspartyl protease, cleaves angiotensinogen to form angiotensin I, which is converted to angiotensin II by angiotensin I converting enzyme, an important regulator of blood pressure and electrolyte balance. Transcript variants that encode different protein isoforms and that arise from alternative splicing and the use of alternative promoters have been described, but their full-length nature has not been determined. Mutations in this gene have been shown to cause familial hyperproreninemia. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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