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Asialoglycoprotein Receptor 2 Rabbit pAb

Cat No.: DPA03546
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Product Name: Asialoglycoprotein Receptor 2 Rabbit pAb
Cat No.: DPA03546
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IP
Recommended Dilution: WB: 1:1000
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Asialoglycoprotein Receptor 2
Calculated Molecular Weight: 35 kDa
Observed Molecular Weight: 45 kDa
GenBank Accession Number: P07307
Gene ID (NCBI): 433
Synonyms: HL-2; HBXBP; ASGPR2; ASGP-R2; CLEC4H2
Background: This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the less abundant minor subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
Category: Primary Ab
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