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Claudin18.2 Rabbit pAb

Cat No.: DPA03643
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Product Name: Claudin18.2 Rabbit pAb
Cat No.: DPA03643
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: IHC
Recommended Dilution: IHC: 1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human Claudin18.2
Calculated Molecular Weight: 28 kDa
GenBank Accession Number: P56856
Gene ID (NCBI): 51208
Synonyms: SFTA5; SFTPJ
Background: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jun 2010]
Category: Primary Ab
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