蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书KCTD21 Rabbit pAb
Cat#:DPA03672应用：WB,FC
| Product Name: | KCTD21 Rabbit pAb |
| Cat No.: | DPA03672 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,FC |
| Recommended Dilution: | WB: 1:1000 FC: 1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | Recombinant protein of human KCTD21 |
| Calculated Molecular Weight: | 30 kDa |
| Observed Molecular Weight: | 30 kDa |
| GenBank Accession Number: | Q4G0X4 |
| Gene ID (NCBI): | 283219 |
| Synonyms: | KCASH2 |
| Background: | Probable substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex mediating the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes the ubiquitination of HDAC1. Can function as antagonist of the Hedgehog pathway by affecting the nuclear transfer of transcription factor GLI1; the function probably occurs via HDAC1 down-regulation, keeping GLI1 acetylated and inactive. Inhibits cell growth and tumorigenicity of medulloblastoma (MDB) (PubMed:21472142). |
| Category: | Primary Ab |
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