DKC1 Rabbit pAb
Cat#:DPA03697应用:WB,ICC/IF
Product Name: | DKC1 Rabbit pAb |
Cat No.: | DPA03697 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,ICC/IF |
Recommended Dilution: | WB: 1:1000-1:5000 ICC/IF: 1:20-1:100 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human DKC1 |
Calculated Molecular Weight: | 58 kDa |
Observed Molecular Weight: | 58 kDa |
GenBank Accession Number: | O60832 |
Gene ID (NCBI): | 1736 |
Synonyms: | DKC; CBF5; DKCX; NAP57; NOLA4; XAP101 |
Background: | This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Category: | Primary Ab |