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TPP1 Rabbit pAb

Cat No.: DPA03748
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Product Name: TPP1 Rabbit pAb
Cat No.: DPA03748
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,IHC
Recommended Dilution: WB: 1:1000-1:2000
IHC: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human TPP1
Calculated Molecular Weight: 61,35 kDa
Observed Molecular Weight: 61,48 kDa
GenBank Accession Number: O14773
Gene ID (NCBI): 1200
Synonyms: CLN2; GIG1; LPIC; SCAR7; TPP-1
Background: This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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