蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书PUMA Rabbit pAb
Cat#:DPA03776应用：WB,IHC,ICC/IF,FC
| Product Name: | PUMA Rabbit pAb |
| Cat No.: | DPA03776 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20-1:100 ICC/IF: 1:50-1:100 FC: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human PUMA |
| Calculated Molecular Weight: | 21 kDa |
| Observed Molecular Weight: | 21 kDa |
| GenBank Accession Number: | Q9BXH1 |
| Gene ID (NCBI): | 27113 |
| Synonyms: | JFY1; PUMA; JFY-1 |
| Background: | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011] |
| Category: | Primary Ab |
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