蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书PMCA1 Rabbit pAb
Cat#:DPA03783应用：WB,IHC
| Product Name: | PMCA1 Rabbit pAb |
| Cat No.: | DPA03783 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC |
| Recommended Dilution: | WB: 1:1000-1:2000 IHC: 1:50-1:200 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human PMCA1 |
| Calculated Molecular Weight: | 139 kDa |
| Observed Molecular Weight: | 130-250 kDa |
| GenBank Accession Number: | P20020 |
| Gene ID (NCBI): | 490 |
| Synonyms: | PMCA1; PMCA1kb |
| Background: | The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 1. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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