SPOP Rabbit pAb
Cat#:DPA03795应用:WB
Product Name: | SPOP Rabbit pAb |
Cat No.: | DPA03795 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human SPOP |
Calculated Molecular Weight: | 42 kDa |
Observed Molecular Weight: | 42 kDa |
GenBank Accession Number: | O43791 |
Gene ID (NCBI): | 8405 |
Synonyms: | TEF2; BTBD32 |
Background: | This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008] |
Category: | Primary Ab |