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NEDD4 Rabbit pAb

Cat No.: DPA03800
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Product Name: NEDD4 Rabbit pAb
Cat No.: DPA03800
Clonality: Polyclonal
Species Reactivity: Human, Mouse, Rat
Tested Applications: WB,FC,IP
Recommended Dilution: WB: 1:2000-1:10000
FC: 1:20
IP: 1:20
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human NEDD4
Calculated Molecular Weight: 149 kDa
Observed Molecular Weight: 115 kDa
GenBank Accession Number: P46934
Gene ID (NCBI): 4734
Synonyms: RPF1; NEDD4-1
Background: This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN. [provided by RefSeq, Jul 2016]
Category: Primary Ab
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