Nuclear Factor Erythroid Derived 2 Rabbit pAb
Cat#:DPA03854应用:WB,IHC,FC
Product Name: | Nuclear Factor Erythroid Derived 2 Rabbit pAb |
Cat No.: | DPA03854 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC,FC |
Recommended Dilution: | WB: 1:1000 IHC: 1:50 FC: 1:100 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human Nuclear Factor Erythroid Derived 2 |
Calculated Molecular Weight: | 42 kDa |
Observed Molecular Weight: | 42 kDa |
GenBank Accession Number: | Q16621 |
Gene ID (NCBI): | 4778 |
Synonyms: | p45; NF-E2 |
Background: | Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron. |
Category: | Primary Ab |