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Nuclear Factor Erythroid Derived 2 Rabbit pAb

Cat No.: DPA03854
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Product Name: Nuclear Factor Erythroid Derived 2 Rabbit pAb
Cat No.: DPA03854
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,FC
Recommended Dilution: WB: 1:1000
IHC: 1:50
FC: 1:100
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human Nuclear Factor Erythroid Derived 2
Calculated Molecular Weight: 42 kDa
Observed Molecular Weight: 42 kDa
GenBank Accession Number: Q16621
Gene ID (NCBI): 4778
Synonyms: p45; NF-E2
Background: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Category: Primary Ab
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