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ADAM15 Rabbit pAb

Cat No.: DPA03872
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Product Name: ADAM15 Rabbit pAb
Cat No.: DPA03872
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC,IP
Recommended Dilution: WB: 1:1000-1:5000
IHC: 1:50-1:200
IP: 1:20-1:50
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: A synthetic peptide of human ADAM15
Calculated Molecular Weight: 93 kDa
Observed Molecular Weight: 93 kDa
GenBank Accession Number: Q13444
Gene ID (NCBI): 8751
Synonyms: MDC15
Background: The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family. ADAM family members are type I transmembrane glycoproteins known to be involved in cell adhesion and proteolytic ectodomain processing of cytokines and adhesion molecules. This protein contains multiple functional domains including a zinc-binding metalloprotease domain, a disintegrin-like domain, as well as a EGF-like domain. Through its disintegrin-like domain, this protein specifically interacts with the integrin beta chain, beta 3. It also interacts with Src family protein-tyrosine kinases in a phosphorylation-dependent manner, suggesting that this protein may function in cell-cell adhesion as well as in cellular signaling. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Category: Primary Ab
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