Cofilin Rabbit pAb
Cat#:DPA02324应用:WB,IHC,ICC/IF,FC
Product Name: | Cofilin Rabbit pAb |
Cat No.: | DPA03981 |
Clonality: | Polyclonal |
Species Reactivity: | Human, Mouse, Rat |
Tested Applications: | WB,IHC,ICC/IF |
Recommended Dilution: | WB: 1:1000 IHC: 1:50 ICC/IF: 1:50 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Cofilin |
Calculated Molecular Weight: | 19 kDa |
Observed Molecular Weight: | 19 kDa |
GenBank Accession Number: | P23528 |
Gene ID (NCBI): | 1072 |
Synonyms: | CFL; cofilin; HEL-S-15 |
Background: | The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskeleton. Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH-dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM, Apr 2004] |
Category: | Primary Ab |