蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书RYK Rabbit pAb
Cat#:DPA04001应用：WB,IHC,ICC/IF,FC,IP
| Product Name: | RYK Rabbit pAb |
| Cat No.: | DPA04001 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:5000-1:10000 IHC: 1:20-1:50 ICC/IF: 1:20-1:50 FC: 1:20 IP: 1:20-1:50 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human RYK |
| Calculated Molecular Weight: | 68 kDa |
| Observed Molecular Weight: | 72 kDa |
| GenBank Accession Number: | P34925 |
| Gene ID (NCBI): | 6259 |
| Synonyms: | JTK5; RYK1; JTK5A; D3S3195 |
| Background: | The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2012] |
| Category: | Primary Ab |
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