Recombinant Oxoguanine Glycosylase 1 (OGG1)
Cat#:TP03247应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Ogg1 Rabbit pAb |
Cat No.: | DPA04075 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:5000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | A synthetic peptide of human Ogg1 |
Calculated Molecular Weight: | 39 kDa |
Observed Molecular Weight: | 39 kDa |
GenBank Accession Number: | O15527 |
Gene ID (NCBI): | 4968 |
Synonyms: | HMMH; MUTM; OGH1; HOGG1 |
Background: | This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008] |
Category: | Primary Ab |