Recombinant Cluster Of Differentiation 276 (CD276)
Cat#:TP04585应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | CD276 Rabbit pAb |
Cat No.: | DPA04171 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB,IHC |
Recommended Dilution: | WB: 1:1000 IHC: 1:500 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human CD276 |
Calculated Molecular Weight: | 57 kDa |
Observed Molecular Weight: | 90-110 kDa |
GenBank Accession Number: | Q5ZPR3 |
Gene ID (NCBI): | 80381 |
Synonyms: | B7H3; B7-H3; B7RP-2; 4Ig-B7-H3 |
Background: | The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011] |
Category: | Primary Ab |