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CD276 Rabbit pAb

Cat No.: DPA04171
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Product Name: CD276 Rabbit pAb
Cat No.: DPA04171
Clonality: Polyclonal
Species Reactivity: Human
Tested Applications: WB,IHC
Recommended Dilution: WB: 1:1000
IHC: 1:500
Size: 30ul 50ul 100uL
Format: Liquid
Source: Rabbit
Purification Method: Affinity Purification
Isotype: IgG
Conjugate: Un-conjugated
Storage: Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a
Immunogen: Recombinant protein of human CD276
Calculated Molecular Weight: 57 kDa
Observed Molecular Weight: 90-110 kDa
GenBank Accession Number: Q5ZPR3
Gene ID (NCBI): 80381
Synonyms: B7H3; B7-H3; B7RP-2; 4Ig-B7-H3
Background: The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Category: Primary Ab
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