Recombinant Human CFD Protein
Cat#:TP01591应用:Positive Control; Immunogen; SDS-PAGE; WB
Product Name: | Factor D Rabbit pAb |
Cat No.: | DPA04238 |
Clonality: | Polyclonal |
Species Reactivity: | Human |
Tested Applications: | WB |
Recommended Dilution: | WB: 1:1000 |
Size: | 30ul 50ul 100uL |
Format: | Liquid |
Source: | Rabbit |
Purification Method: | Affinity Purification |
Isotype: | IgG |
Conjugate: | Un-conjugated |
Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
Immunogen: | Recombinant protein of human Factor D |
Calculated Molecular Weight: | 27 kDa |
Observed Molecular Weight: | 27 kDa |
GenBank Accession Number: | P00746 |
Gene ID (NCBI): | 1675 |
Synonyms: | DF; ADN; PFD; ADIPSIN |
Background: | This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015] |
Category: | Primary Ab |