蛋白
抗体
检测试剂盒
蛋白MARKER
分子生物学
规格：
查看说明书Recombinant Human BLNK Protein
Cat#:TP01344应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | BLNK Rabbit pAb |
| Cat No.: | DPA04317 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,IP |
| Recommended Dilution: | WB: 1:1000 IHC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human BLNK |
| Calculated Molecular Weight: | 51 kDa |
| Observed Molecular Weight: | 70 kDa |
| GenBank Accession Number: | Q8WV28 |
| Gene ID (NCBI): | 29760 |
| Synonyms: | bca; AGM4; BASH; LY57; SLP65; BLNK-S; SLP-65 |
| Background: | This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012] |
| Category: | Primary Ab |
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