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查看说明书Recombinant Human HDAC3 / Histone deacetylase 3 Protein (His & GST tag)
Cat#:TP07065应用：Positive Control; Immunogen; SDS-PAGE; WB
| Product Name: | HDAC3 Rabbit pAb |
| Cat No.: | DPA04400 |
| Clonality: | Polyclonal |
| Species Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB,IHC,ICC/IF,FC,IP |
| Recommended Dilution: | WB: 1:1000-1:5000 IHC: 1:20 ICC/IF: 1:50-1:200 FC: 1:20 IP: 1:20 |
| Size: | 30ul 50ul 100uL |
| Format: | Liquid |
| Source: | Rabbit |
| Purification Method: | Affinity Purification |
| Isotype: | IgG |
| Conjugate: | Un-conjugated |
| Storage: | Store at -20°C. Supplied in 50nM Tris-Glycine(pH 7.4), 0.15M NaCl, 40%Glycerol, 0.01% sodium azide a |
| Immunogen: | A synthetic peptide of human HDAC3 |
| Calculated Molecular Weight: | 49 kDa |
| Observed Molecular Weight: | 49 kDa |
| GenBank Accession Number: | O15379 |
| Gene ID (NCBI): | 8841 |
| Synonyms: | HD3; RPD3; RPD3-2 |
| Background: | Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008] |
| Category: | Primary Ab |
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